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You could try Yamato Nadeshiko Shichi Henge , also known as The Wallflower , it's fresh, original and a really funny romance. Also, the drama they did from it was really damn good.
Skip Beat! is funny, romantic, complex.
As for gender benders, try Ageha 100% and Kira Kira Labyrinth. They've both got a solid romance and neither is ecchi.
Also, all of my recommendations so far are school life.
You could try M to N no shouzou , the art is really pretty and the story is rather funny and cute.
Also, if you don't mind the Supernatural stories, you could try Tarot Cafe , albeit some arcs could get disturbing and I think because of one story arc has "yaoi" in it's genre description. The romance is gorgeous. It only fits into the "romance" tag of everything you've got there, but it's worth a try.
I really had to cut back on my recommendations because of the no ecchi thing. sad

You're welcome! I was glad I could help!

Angel Densetsu is a good comedy, just bear with the art, it's the mangaka's early work (he went on to do claymore)
Hole (the third one shot here) is a good one. It's.. bitter sweet.
black cat Is also pretty funny.

Angel and black cat are both shounen, so I'm not sure how into them you'll be, but give them a shot. Oh, and if you get sick of the shoujo female leads being dumb (which happens in some of them, lets face it.) THIS Trust me, you won't see the end coming.